Los Angeles Chargers running back Najee Harris suffered a brutal lower-leg injury in the second quarter of their AFC West divisional matchup against the Denver Broncos on Sunday.Harris was lined up behind quarterback Justin Herbert as the play got started with 5:16 left in the half. Herbert faked the handoff, and Harris immediately went down grabbing his left foot. A replay showed Harris trying to push off his left foot before a shockwave was sent up his leg.CLICK HERE FOR MORE SPORTS COVERAGE ON FOXNEWS.COMHe went down immediately on the non-contact play.Harris was seen being carted off the field. The Chargers initially said he was questionable to return with an ankle injury, but he was later downgraded to out.WARNING: GRAPHIC VIDEOChargers head coach Jim Harbaugh didnt have an immediate update when he spoke to CBS before the start of the third quarter.VIKINGS' ISAIAH RODGERS MAKES NFL HISTORY WITH UNPRECEDENTED DEFENSIVE PERFORMANCE AGAINST BENGALSLos Angeles signed Harris in the offseason after he spent the first four years of his career with the Pittsburgh Steelers. He was set to be a part of a backfield with Omarion Hampton. The injury will certainly be a blow to the Chargers offense.Harris rushed for 1,043 yards and six touchdowns in 2024 the fourth consecutive year he reached at least 1,000 rushing yards. He hadnt missed a single game since his rookie season.He had 28 rushing yards on six carries before he left the game.Follow Fox News Digitalssports coverage on X and subscribe to the Fox News Sports Huddle newsletter.