President Donald Trump targeted Sen. Susan Collins, R-Maine, in a Thursday night Truth Social post, urging Republicans to vote in the opposite of the way that she does."Republicans, when in doubt, vote the exact opposite of Senator Susan Collins. Generally speaking, you cant go wrong. Thank you for your attention to this matter and, MAKE AMERICA GREAT AGAIN!" the president declared in the post.Fox News Digital reached out to Collins' office early on Friday morning to request a comment from the senator.TWO REPUBLICANS VOTE AGAINST TRUMP'S $9 BILLION CLAWBACK OF FOREIGN AID, NPR FUNDINGLast month Collins voted against passage of the One Big Beautiful Bill Act and against passage of a rescissions measure, both of which Trump ultimately signed.Earlier this year she voted against confirming Pete Hegseth to serve as secretary of defense and against confirming Kash Patel to serve as FBI director.SENATE PASSES TRUMP'S BIG, BEAUTIFUL BILL AFTER MARATHON VOTE-A-RAMAIn February 2021, she voted to convict Trump after the House impeached him in the wake of the Jan. 6, 2021 Capitol riot, but that Senate vote, which occurred after Trump had already departed from office, did not reach the threshold necessary for conviction.SUSAN COLLINS VOWS TO OPPOSE TRUMP FBI DIRECTOR NOMINEE KASH PATEL AHEAD OF CRITICAL VOTECollins has served in the Senate since 1997.